Zones of maximum discontinuity in the western house mouse (M. m. domesticus) genetic landscape: a computational geometry method

Fatah Zarei1 & Ridha H. Hussein2*

1 Graduate Student of Systematic Zoology, Faculty of Biological Sciences, Shahid Beheshti University-Tehran, Iran
2 Zoology Assistant Professor, Department of Biology, School of Science, Sulaimani University, Sulaymaniyah-Iraq

Original: 11.09.2015Revised: 05.01.2015Accepted: 30.01.2015Published online: 20.06.2016

DOI Link: 


To represent the zones of maximum genetic discontinuity in a network of geographically located populations of western house mouse from the previously published mitochondrial DNA D-loop sequence datasets which we acquired from the NCBI GenBank database, we applied a computational geometry approach using the Monmonier’s maximum difference algorithm implemented in the BARRIER 2.2 software. We defined ten zones where genetic change among populations is locally increased, three of them occur within the Middle East, while seven occur in Europe. Analysis of molecular variance among post-hoc defined regions using the pattern generated by the BARRIER analysis showed that a significant.


BARRIER analysis

Genetic discontinuity

Monmonier’s algorithm

Western house mouse