Prevalence of Helicobacter Pylori among Dyspeptic Patients


Ali Yahya Saeed, & Safar Mohammad Pedawi

College of Medicine, University of Duhok




Abstract
A total of 150 biopsies were collected from, dyspeptic patients  dyspeptic patients with and without ulcers from endoscopic unit of Azadi hospital, Dohuk.
This study found a hiqh percentage (64%r) of Helicobacter pylori in the antrum of dyspeptic patients without endoscopic ulcers, while much lower, percentage was
found in dyspeptic patients with gastric and duodenal ulcers which was (33%) and (20%) respectively. This low level of percentage was attributed to the inhibitory 
effect of antibiotics (Metronidazole,'Amoxicillin, Tetracyline) which received by (70%) of patients prior endoscopic examination. Tie study detected a high association 
(75%) between Helicobacter pylori and patients with chronic active duodenol ulcer Rapid urase test was more reliable tian direct smear for detection of H. pylori,
which- can be employed as ascreening test. Helicobacter pylori can be grown anaerobically for at least five days incubation at 37 Co by using selective
antibiotics to prevent contamination and without providing gas mixture 85% N2, 10% Co2 and 5% O2 which was used in all previous studies.

Keywords: Helicobacter pylori, Dyspepsia


References

1-ATR Axon: Helicobacler pylori its role in gastrointestinal disease,1994 Science Press Leeds,UK,.
2-Connor F O, Buckley M.: Helicobacter pylori and the cancer Link. Journal of the Royal Society of Medicine, 1996, 89, 674-677 .
3-Gabriel Virella, Microbiology and Iniectious disease. l997 3rd ed, williams and wilkins. U.S.A..
4-Goodwin CS, Blincow WD, Warren JR, Waters TE, Sanderson CR.: Evaluation of cultural techniques for isolating compylobacte pyloridis from endoscopic biopsies of gastric mucosea. J .Clin, Pathol. 1985,38,1127-1131'
5-Goodwin-CS, Armstrong JA, Chilvers T: Transfer of Campylobacter pylori and campylobacter mustelae to Helicobacter pylori-Int J syst Bocteriology.
 1989,39,397-405.
6-Jawet, Z, et al: Medical Microbiology 20th ed. Alange Medical book 1995:229- 230 Norwalk.
7-Koneman EW, Allen SD, Schreckenberger P; color altas and textbook of diagnostic microbiology,l992,4th ed. J.B Lippin cott company, philadelphia.
8-Lee A: Helicoater Pylori and Helicobacter like organsim in animals' In Helocobecter Pylori and Gastroduodenal disease. 1992, 2nd ed. Edited by Rathbone Bj Healthy Rv. Oxford. Blackwell scientific publications:259-275.
9-Marshall BJ: unidentified curved bacillus on gastric epithelium in active chronic gastritis. Lancet 1983, 1,1243 -1275.
10-Marshall BJ, Warren JR: unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet 1984, 1, 1311 - 1315.
11-Schneider RE, Torr, M et al A simple method to detect Helicobacter pylori in gastric biopsy. BJM, 1990, 300,1559.
12-peter Hawker. Peptic ulcer disease. The practitioner, 1989 ,769-773.
13-Warren JR: unidentiJied curved bacilli on gastric epithelium in chronic active gostritis. Lancet 1983, 1,1273.