Acute toxicity of Pistacia atlantica green seeds on Sprague- Dawley rat model

Authors

  • Hiewa Othman Dyary College of Veterinary Medicine, University of Sulaimani, Kurdistan Region, Iraq. Author
  • Heshu Sulaiman Rahman College of Veterinary Medicine, University of Sulaimani, Kurdistan Region, Iraq. & Department of Medical Laboratory Science, College of Health Science, Komar University of Science and Technology, Sulaimani, Kurdistan Region, Iraq. & Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia. Author
  • Hemn Hassan Othman College of Veterinary Medicine, University of Sulaimani, Kurdistan Region, Iraq. & Department of Medical Laboratory Science, College of Health Science, Komar University of Science and Technology, Sulaimani, Kurdistan Region, Iraq. & Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia. Author
  • Snur Mohammad Amen Hassan College of Veterinary Medicine, University of Sulaimani, Kurdistan Region, Iraq. Author
  • Rasedee Abdullah Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia. Author

DOI:

https://doi.org/10.17656/jzs.10628

Keywords:

Pistacia atlantica, Acute toxicity, Animal model, Mount Atlas mastic tree

Abstract

The acute toxic effect of the aqueous extract of Pistacia atlantica green seeds was investigated in groups of Sprague-Dawley rats at oral doses of 200, 400, and 800 mg/kg body weight. After 14 days, there was no significant difference (p>0.05) in behavior, food and water consumption, body weight gain, and hematological and serum biochemical parameters between untreated control and extract-treated rats. There were lesions in the liver and kidney indicating that aqueous P. atlantica seed extract causes some hepatoxicity and nephrotoxicity in rats.

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Published

2017-11-22

How to Cite

Acute toxicity of Pistacia atlantica green seeds on Sprague- Dawley rat model. (2017). Journal of Zankoy Sulaimani - Part A, 19(3-4), 9-16. https://doi.org/10.17656/jzs.10628

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